PCOS and Metabolic Dysfunction: Why Early Diagnosis Matters

29 May

Polycystic Ovary Syndrome (PCOS) is often misunderstood as purely a reproductive condition. However, at Arise Wellness Clinic, we emphasize that PCOS is also a metabolic disorder with significant systemic implications. Recognizing and treating PCOS early can prevent complications like diabetes, cardiovascular disease, and infertility.

Understanding PCOS PCOS affects approximately 1 in 10 women of reproductive age. It is diagnosed based on at least two of the following:

  • Irregular menstrual cycles
  • Clinical or biochemical signs of hyperandrogenism (e.g., hirsutism, acne)
  • Polycystic ovaries on ultrasound

The Metabolic Side of PCOS Insulin resistance is a central feature of PCOS, even in lean women. Elevated insulin levels stimulate ovarian theca cells to produce more androgens, worsening hormonal imbalances. High insulin also inhibits liver production of sex hormone-binding globulin (SHBG), increasing free testosterone levels.

Impact on Weight and Metabolism Women with PCOS often struggle with weight gain and have difficulty losing weight. Studies show that up to 70% of women with PCOS are insulin resistant, contributing to increased risk for:

  • Type 2 diabetes
  • Dyslipidemia
  • Hypertension

Research Findings A 2017 review in Human Reproduction Update found that early diagnosis and management of PCOS could reduce long-term metabolic risks. Another study in Fertility and Sterility (2019) emphasized the role of insulin-sensitizing therapies in improving both reproductive and metabolic outcomes.

Early Diagnosis and Intervention Early diagnosis allows for interventions that can mitigate long-term complications:

  • Lifestyle modifications: Diet and exercise can improve insulin sensitivity and regulate menstrual cycles.
  • Medications: Metformin, oral contraceptives, and anti-androgens can help manage symptoms.
  • Psychological support: Addressing mental health is crucial due to higher rates of anxiety and depression in women with PCOS.

Conclusion PCOS is a multifaceted condition with significant metabolic implications. At Arise Wellness Clinic, our integrative approach targets the root causes, helping women achieve hormonal balance, metabolic health, and improved quality of life.

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