Prediabetes is a critical warning sign—a chance to prevent type 2 diabetes before it takes hold. At Arise Wellness Clinic, we focus on early identification and intervention using the latest scientific evidence to reverse this trajectory.
What is Prediabetes? Prediabetes occurs when blood glucose levels are elevated but not yet high enough to be classified as diabetes. Criteria include:
- Fasting glucose: 100–125 mg/dL
- HbA1c: 5.7%–6.4%
- Impaired glucose tolerance test (OGTT): 140–199 mg/dL at 2 hours
Pathophysiology Prediabetes is marked by insulin resistance and impaired beta-cell function. As insulin becomes less effective, glucose builds up in the bloodstream. Over time, the pancreas cannot keep up with insulin demand.
Evidence-Based Interventions
- Diet: Low-carbohydrate, high-fiber diets reduce postprandial glucose spikes.
- Exercise: Improves insulin sensitivity and lowers fasting glucose.
- Weight loss: Even a 5–7% reduction in body weight can significantly lower risk.
- Medication: Metformin has been shown to delay or prevent progression, especially in younger, heavier individuals.
Clinical Evidence The landmark Diabetes Prevention Program (DPP) study demonstrated that lifestyle changes reduced the risk of developing diabetes by 58%, compared to 31% with metformin. Follow-up studies have shown that these benefits can be sustained long-term.
Patient Empowerment Education and self-monitoring are key. Tools such as continuous glucose monitors (CGMs) and mobile health apps can enhance engagement and accountability.
Conclusion Prediabetes is not a permanent state—it’s a call to action. At Arise Wellness Clinic, we empower patients with the tools, knowledge, and support they need to take control of their metabolic health and prevent type 2 diabetes.
